Anti-proliferative activity of green tea extract in Human Cervical Cancer Cells (HeLa)
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Date
2013
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Abstract
In this study mitiproliferative effect of Green tea extract was evaluated on HeLa
cell line. HeLa cells were cultured in DMEM medium and incubated witli different
concentrations (18.75, 37.5, 75, 150 and 300 gg/ml) of methanol extract of Green
tea. Cell viability was assessed by MTT assay. Green tea decreased cell viability in
malignant cells in a concentration dependent manner. The IC50 value of green tea
extract was found to be 111.9pg/inl. It may be concluded that green tea could cause
cell death in HeLa cells and can be considered as a promising antiproliferative
agent against cervical carcinogenesis.
Introduction
Cancer