Browsing by Author "Jeyanthi, G P"
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- ItemAdsorption of Mckel(Ii) and Chromium(Vi) from Synthetic Metal Solutions Using Powdered Human Hair as Adsorbent(2010) Jeyanthi, G PAdsorption is one of tlie elTective techniques f6r the removal of nickel(II) and chromium (VI) from waste water. In this study, adsorbent is prepared from human hair and studies were carried out for the removal o f nickel (II) and chromium (VI) from synthetic metal solutions. Batch adsorption stud ies demonstrate that the adsorbent prepared from human hair has a significant capacity for adsorption of nickel (II) and chromium (VI) fi'om synthetic metal solution and for the removal of nickel (II) and chromium (VI) from synthetic binary metal solution. The parameters investigated in this study include pH, temperature, adsorbent dosage, initial concentration and contact time. The adsorption process of nickel (II) and chromium (VI) are tested with Langmuir and Freundlich isothemi models. The maximum adsor|rtion capacity of nickel (II) was found to be pH 6 (52.2 %) and chromium (VI) was at pH 4 (74 %) in room temperature from synthetic metal solution. The maximum removal of nickel (11) (48.2 %) and chromium (VI) (54.9 %) were found to be at pH 4 in room temperature from synthetic binary metal solution.
- ItemAir Quality Monitoring and Health Surveillance of Photocopier Service Personnel in Xerographic Units(2016-03) Vallikkannu, K; Jeyanthi, G P
- ItemAlpha-amylase and alpha-glucosidase inhibitory property and antioxidant potential of Polyalthia longifolia bark extracts(2012) Jeyanthi, G PDiabetes mellitus is a metabolic disorder characterized by hyperglycemia and it is one of the free radical mediated ailments. Among the various anti-diabetic therapeutic approaches one major strategy is reducing gastrointestinal absorption of glucose by inhibition of carbohydrate metabolizing enzymes alpha-amylase and alpha-glucosidase In the present study the aqueous extracts of Polyalthia longifolia bark has been assessed for the inhibition of alpha-amylase and alpha-glucosidase and total antioxidant potential (FRAP assay). In vitro antioxidant activity of the ethanol extract (polar solvent) and hexane extract (non-polar solvent) has been assessed using various antioxidant model systems, viz DPPH, ABTS, NO, OH, SO and inhibition of in vitro lipid peroxidation. The aqueous extract of the bark exhibits highest alpha-amylase and alpha-glucosidase inhibition. Ethanol extract of Polyalthia longifolia is found to possess highest DPPH, ABTS, nitric oxide, hydroxyl, superoxide scavenging activity at lower concentration compared to the hexane extract. Also the ethanolic extract of Polyalthia longifolia is found to be good inhibitor of in vitro lipid peroxidation. Saturation in the enzyme inhibition and free radical scavenging activity has been attained in a concentration dependent manner. This study indicates significant alphaamylase and alpha-glucosidase inhibition, free radical scavenging potential and lipid peroxidation inhibition of Polyalthia longifolia bark which can be exploited for the treatment of various free radical mediated diseases like diabetes mellitus. Studies are being done on the various solvent extracts of the bark for enzyme inhibition to isolate the active compounds with potent inhibition for alpha-amylase, alpha-glucosidase and antioxidant potential.
- ItemAnalysis of Expression of Heat Shock Protein-70 (Hsp-70) Gene in Salt Stressed Groundnut (Arachis Hypogaea L.) Plants(2011) Jeyanthi, G P; Indhuleka, AQuantitative real-time PCR (RT-PCR) has already been used to study the expression profile of several plant gene families. This study demonstrates the potential of RT-PCR to measure the expression of heat shock protein (HSP) genes in groundnut {Arachis hypogaea L.) that underwent salt stress followed by RT-PCR of hsp70 mRNA using the housekeeping gene tubulin {tub) as a reference gene and the fluorogenic dye SYBR Green I. Expression of HSP70 gene was identified in salt stressed groundnut genotype TMV7.
- ItemAssessment of Biochemical and Toxicological Effects of the Effluents of Tirupur Textile Units and Evolving Simple Biological Methods to Depollute them(1994-02) Jeyanthi, G P; Janabai Giri
- ItemAssessment of Renal and Pulmonary Functions Among Gold Jewellery Workers(2011-04) Annapoorani, A N; Jeyanthi, G P
- ItemBiochemical Changes in Breast Cancer(1989-04) Jayanthi, P; Jeyanthi, G P
- ItemBiochemical Profile and Characterisation of Proteins in the Lens Extracted from Human Cataractous Subjects(2014-07) Sreeja, S; Jeyanthi, G P
- ItemBiochemical Profile and Pulmonary Function in Ginning Factory Women Labourers Exposed to Cotton Dust Pollution at Triupur(2001-10) Jannet Vennila, J; Jeyanthi, G P
- ItemBioremediation of Chromium (VI) from Tannery Effluents using Selected Bacterial and Fungal Isolates and Agrowaste Adsorbents(2003-11) Selvi, V; Jeyanthi, G P
- ItemCardiac Biomarkers and Atherogenic Indices in Hypertensive Postmenopausal Women With Co-Morbidities(2014) Jeyanthi, G PPostmenopausal women are susceptible to various non-communicable diseases. Hypertension and hyperlipidemia contribute significantly to atherosclerotic cardiovascular disease. Hence, the present study was carried out to assess cardiac biomarkers and atherogenic indices in four groups of postmenopausal women namely norrnotensive postmenopausal women, hypertensive postmenopausal women, hypertensive postmenopausal women with diabetes and hypertensive postmenopausal women with renal insufficiency. Total cholesterol, HDL-cholesterol, triglyceride, VLDL-cholesterol and LDL-cholesterol were assessed in the subjects. Atherogenic index (LDl C/HDL-C), cardiac risk ratio (TC/HDL-C), atherogenic coefficient ((TC-HDL)/HDL) and atherogenic index ol plasma (log (TG/HDL C)) were calculated in the participants of the study. One way ANOVA and Kruskal Wallis test were performed. Statistical analysis was performed using SPSS16.0 statistical software. Total cholesterol was significantly increased in hypertensive postmenopausal women compared to the other groups namely hypertensive postmenopausal women with diabetes, hypertensive postmenopausal women with renal insulficiency and norrnotensive postmenopausal women. HDL-cholesterol was significantly decreased in hypertensive postmenopausal women witn renal insufficiency compared to the other three groups. Triglycerides and VLDL-choiesterol vyere significantly increased in hypertensive postmenopausal women compared to the control group. LDl.-cfiolesterol was significantly increased in experimental groups compared to norrnotensive control group. Atherogenic index, atherogenic coefficient, cardiac risk ratio and atherogenic index of plasma were significantly increased in experimental groups compared to norrnotensive postmenopausal women. Reduced levels of HDL cholesterol and elevated levels of other cardiac biomarkers and atherogenic indices reflected the onset/progression of atherosclerotic cardiovascular disease in hypertensive postmenopausal women with and without co-morbidities.
- ItemChronic exposure to emissions from photocopiers in copy shops causes oxidative stress and systematic inflammation among photocopier operators in India(2013) Jeyanthi, G PBackground: We assessed indoor air quality in photocopier centers and investigated whether occupational exposure to emissions from photocopiers is associated with decline in lung function or changes in haematological parameters, oxidative stress and inflammatory status. Methods: Indoor air quality was monitored in five photocopier centers. Pulmonary function was assessed by spirometry in 81 photocopier operators (64 male and 17 female) and 43 healthy control (31 male and 12 female) subjects. Hematological status, serum thio-barbituric acid reactive substances (TBARS), total ferric reducing antioxidant capacity (FRAC), leukotriene (LT3.,), 8-isoprostane, C reactive protein (CRP), interleukin 8 (IL-8), data cell protein (CC-16), intercellular adhesion molecule 1 (ICAM-1) and eosinophilic cationic protein (ECP) were analyzed. Relationships between cumulative exposure, lung function and inflammatory markers were assessed. Results: PMio and PM;,.s were above the permissible levels in all the photocopier centers, whereas the levels of carbon monoxide, nitrogen oxides, ozone, sulphur dioxide, lead, arsenic, nickel, ammonia, benzene and benzo(a) pyrene were within Indian ambient air quaiity standards. Lung furiction was similar in the photocopier operators and control subjects. Serum TBARS was significantly higher and FRAC was lower among photocopier operators when compared to healthy controls. Plasma IL-8, LTB^, ICAM-1 and ECP were significantly higher in the photocopier exposed groui:.'. Conclusions: Photocopiers emit hign of part culate matter. Long term exposure to emissions from photocopiers was not associated witn decreased lung function, but resulted in high oxidative stress and systemic inflammation leading to high risk of cardiov.ascuiar diseases.
- ItemComparative Study on the Antidiabetic Potential of Alpha Amylase Inhibitors in Momordica Charantia and Trigonella Foenum Graecum(2017-06) Renuka, R; Jeyanthi, G P
- ItemEffect of Phytase and Citric Acid Supplementation on the Growth Performance, Phosphorus, Calcium and Nitrogen Retention on Broiler Chicks Fed with Low Level of Available Phosphorus(2011) Jeyanthi, G PAn experiment was conducted to study the effect of phyt.ase and citric acid on the growth perforinance, phosphorus, calcium and nitrogen retention with sixty 1 day old mixed sex broiler chicks for 42 days. The expennient consists of four treatments with three replicates and live chicks in each implicate. The treatments were; Tl-control diet (0.3% available phosphorus), T2-control diet with 2% citric acid, T3-control diet with 8(X) IJ pliyd.ase enzyme. T4-control diet with 800 k.l phytase plus 2% citric acid. The results revealed that tlie weight gam of the chicks was significantly liigher (p<0.05) for groups t.hat received phytase and phytase |Jiis cil.nc acid supjilementation. Feed intake and feed conversion ratio were significantly higher for group that received both phytase and citric acid. Phytase and citric acid supplementation indmdually and in combination signilieantly improved phosphorus retention. Calcium and nitrogen retention were significantly higher for groups that received supplementation of phytase and pliytase plus citric acid. Mo significant difference in phosphorus and calcium content of toe samples were observed between broilers of different diets.
- ItemThe Effect of Supplementation of Diet With Vitamin-E and Selenium and their Combinations on the Performance and Lipid Profiles of Layer Chickens(2010) Jeyanthi, G PA biological experiment was conducted to study the effect of vitamin E and selenium supplementation on growth performance and lipid profile with two hundred and ten commercial straight run day-older layer chicks. The chicks were randomly allotted into seven treatment groups with three replicates of ten chicks each. The chicks were fed basal diet (Ti), basal diet with 100mg/kg vitamin E (T2 ), basal diet with 200mg/kg vitamin E (T3), basal diet with 0.2mg/kg selenium (T4), basal diet with 0.4mg/kg selenium (T5), basal diet with 100mg/kg vitamin E plus 0.2mg/kg selenium (T6), and basal diet with 200rng/kg vitamin E plus 0.4mg/kg selenium (T7) for thirty two weeks period. The results revealed that there was no significant difference in body weight of layer chicks for the first four weeks between treatment groups but the body weight of groups (T6 and T7) receiving both vitamin E and selenium supplementation is significantly increased (P<0.05) during 5-32 weeks period of age. The feed intake of layer chicks did not vary significantly between treatment groups. Chicks receiving supplements of both vitamin E and selenium produced significantly (P<0.01) lower total cholesterol, triglycerides, VLDL and LDL cholesterol and significantly higher (P<0.01) HDL cholesterol. Present research suggested that vitamin E and selenium influences lipid metabolism by decreasing total cholesterol, triglycerides, VLDL and LDL cholesterol and increasing HDL cholesterol.
- ItemThe Effect of Supplementation of Diet With Vitamin-E And Selenium and their Combinations on the Performance and Lipid Profiles of Layer Chickens(2010) Jeyanthi, G PA biological experiment was conducted to study the effect of vitamin E and selenium supplementation on growth performance and lipid profile with two hundred and ten commercial straight run day-older layer chicks. The chicks were randomly allotted into seven treatment groups with three replicates of ten chicks each. The chicks were fed basal diet (T|), basal diet with lOOmg/kg vitamin E (T2), basal diet with 200mg/kg vitamin E (T3), basal diet with 0.2mg/kg selenium (T4), basal diet with 0.4mg/kg selenium (T5), basal diet with lOOmg/kg vitamin E plus 0.2mg/kg selenium (T6), and basal diet with 200mg/kg vitamin E plus 0.4mg/kg selenium (T7) for thirty two weeks period. The results revealed that there was no significant difference in body weight of layer chicks for the first four weeks between treatment groups but the body weight of groups (Tf, and T7) receiving both vitamin E and selenium supplementation is significantly increased (P<0.05) during 5-32 weeks period ot age. The feed intake of layer chicks did not vary significantly between treatment groups. Chicks receiving supplements of both vitamin E and selenium produced significantly (P<0.01) lower total cholesterol, triglycerides, VLDL and LDL cholesterol and significantly higher (P<0.01) HDL cholesterol. Present research suggested that vitamin E and selenium influences lipid metabolism by decreasing total cholesterol, triglycerides, VLDL and LDL cholesterol and increasing HDL cholesterol.
- ItemEvaluation of Renal Status among Hypertensive Postmenopausal Women with and without Renal Insufficiency(2014) Jeyanthi, G PMenopause is accompanied by increased risk of chronic diseases. Hypertension is mostly asymptomatic and if left untreated may progress to renal damage. In the present study, an attempt was made to as.sess the renal function among hypertensive postmenopau.sal women with and without renal insufficiency. Forty five postmenopausal women were selected and categorized into three groups - normolensive postmenopausal, hypertensive postmenopausal and hypertensive postmenopau.sal with renal insufficiency. Serum sodium, potassium, chloride, creatinine and estimated glomerular filtration rate were assessed in the selected groups. One way ANOVA and Kruskal-Wallis test were performed using SPSS 16.0 statistical .software. Sodium levels were significantly elevated in hypertensive postmenopausal women compared to those with renal insufficiency. Whereas potassium levels were significantly decreased in hypertensive postmenopausal women compared to normotensives. No significant difference was observed in chloride levels. Serum creatinine levels were significantly increased in hypertensive postmenopausal with renal insufficiency compared to normotensive and hypertensive postmenopau.sal women. A significant decline in estimated glomerular filtration rate was found in experimental groups compared to normotensive control. Elevated levels of creatinine and drop in estimated glomerular filtration rate reflected impaired renal jimction. Elevated sodium and decreased potassium levels in hypertensives might indicate the intake of high sodium and low potassium diet as contributing factor for the development o f hypertension.
- ItemFree Radical Scavenging Activity of Metallothioneins from Peripheral Blood Lymphocytes of Gold Jewellery Karigars(2014) Jeyanthi, G PMetallothioneins (MT) are cysteine rich, low molecular weight metal binding proteins involved in deto.xification and homeostasis of metals. Due to a variety of chemical stresses MTs are stimulated and can be used to assess human exposure to occupational agents. Human Peripheral Blood Lymphocytes (PBLs) have the ability to produce MTs against occupational exposure to silver (Ag). In the present study. PBLs were isolated from the blood of gold jewellery unit workers and MT was separated by sephade.x G-75 gel filtration. Molecular mass of MT was determined by SDS-PAGE using silver staining method from the collected fractions. HPLC was performed to measure the levels of MT from the collected fraction, it is suggested that the elevated levels of MT in PBLx can he used as specific indices of .silver e.xposure.
- ItemInfluence of Vitamin-E and Selenium Supplementation on the Growth Performance and Antibody Responses of Layer(2010) Jeyanthi, G PAn experiment was conducted to study the effect of vitamin E and selenium yeast supplementation on the growth performance and some immune parameters with two hundred and ten commercial straight run day-older layer chicks. The chicks were randomly allotted into seven treatment groups with three replicates often chicks each. The chicks were fed basal diet (Ti), basal diet with 100 mg/kg vitamin E (T2), basal diet with 200 mg/kg vitamin E (T?), basal diet with 0.2 mg/kg selenium (T4), ba.sal diet with 0.4 mg/kg selenium (T5), basal diet with 100 mg/kg vitamin E plus 0.2 mg/kg selenium (T(,), and basal diet with 200 mg/kg vitamin E plus 0.4 mg/kg selenium (T?) for eight weeks period. No significant difference was found in the body weight of layer chicks for the first four weeks among the treatment groups but the body weight ofgroups (T* and T7) receiving both vitamin E and selenium was significantly increased {P<0.05) at the end of 8 weeks period. The feed intake of layer chicks did not vary significantly between treatment groups. Chicks receiving supplements of 100 mg vitamin E/kg and 0-2 mg selenium/kg produced significantly higher HA litre against SRBC (P<0.0/), HI litre against NDV (P<0.0J) and QAGPT litre against IBDV {P<0.()i). The results suggested that vitamin E and selenium might provide higher level of protection against natural immune challenges.