Bioassay Guided Fractionation and Antifungal Activity Studies on Pisonia grandis R .B R .
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Date
2010
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Abstract
Pisonia grandis is an herb claimed to be used for treatment of various diseases
by local folks. Since, this plant possesses many medicinal properties; there are
not many scientific studies carried out on this plant which promoted us to pursue
a systematic pharmacological evaluation of Pisonia grandis leaves to verify their
medicinal properties. Bioassay- guided fractionation of ethanol extract of leaves
of Pisonia grandis was studied for its anti-fungal activity against
microorganisms Candida albicans, Aspergillus niger, Pencillium citrinum and
Monascuspiirpureiis by disc diffusion method. The ethanol extract showed good
anti-flingal activity against Monascus purpureas comparable to standard
clotrimazole.