Evaluation of Renal Status among Hypertensive Postmenopausal Women with and without Renal Insufficiency
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Date
2014
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Abstract
Menopause is accompanied by increased risk of chronic diseases. Hypertension is mostly asymptomatic and if left untreated
may progress to renal damage. In the present study, an attempt was made to as.sess the renal function among hypertensive
postmenopau.sal women with and without renal insufficiency. Forty five postmenopausal women were selected and
categorized into three groups - normolensive postmenopausal, hypertensive postmenopausal and hypertensive
postmenopau.sal with renal insufficiency. Serum sodium, potassium, chloride, creatinine and estimated glomerular filtration
rate were assessed in the selected groups. One way ANOVA and Kruskal-Wallis test were performed using SPSS 16.0
statistical .software. Sodium levels were significantly elevated in hypertensive postmenopausal women compared to those
with renal insufficiency. Whereas potassium levels were significantly decreased in hypertensive postmenopausal women
compared to normotensives. No significant difference was observed in chloride levels. Serum creatinine levels were
significantly increased in hypertensive postmenopausal with renal insufficiency compared to normotensive and hypertensive
postmenopau.sal women. A significant decline in estimated glomerular filtration rate was found in experimental groups
compared to normotensive control. Elevated levels of creatinine and drop in estimated glomerular filtration rate reflected
impaired renal jimction. Elevated sodium and decreased potassium levels in hypertensives might indicate the intake of high
sodium and low potassium diet as contributing factor for the development o f hypertension.