Antifungal Activity of Few Nitrogen Heterocycles Synthesized Under Microwave Irradiation
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Date
2010
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Abstract
Quinoline compounds possess a wide range of
antibacterial, antifungal and antimutagenic properties. The
present work involves synthesis of three heterocycles-4-
Phenyl 3-vinyl quinolin-2-one (1). 4-phenyl-3-chloroquinoline
(2), 4-phenyl-3-vinyl quinoline-2-thione (3)
utilizing microwave technology and testing their antifungal
activity against 4 fungi namely Aspergillus flavus, Rhizopus
nigricans, Mucor hiemalis and Candida albicans. Antifungal
studies of compounds showed good fungal activify. The
antimicrobial significance of the synthesized compounds is
well evident from the study.