Browsing by Author "Gayathri Devi, S"

Now showing 1 - 20 of 31
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    Antibacterial Activity of Helicteresisora
    (2012) Gayathri Devi, S
    Helicteres isora belongs to the family Stcrciiliaceac is an ayurvedic herb. It i.s distributed widely in forest throughout India and are commonly known as Indian Screw tree, is a medicinally important sub-deciduous shrub or small tree. Almost all parts of the plants are used in traditional medicinal system for curing various diseases. Because of its wide usage and availability, this study was set out to investigate the antibacterial activity of the plant. Petroleum ether, chlorofomi, benzene, acetone and methanol extracts of both the fruit and bark of Helicteres isora exhibited varying degrees of antibacterial activity when tested with eight bacterial strains.
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    Antibacterial Activity of Leaves and Roots of Eclipta Alba
    (2014) Gayathri Devi, S
    Objective: The present study was aimed to investigate the antibacterial activity of leaves and roots of Eclipta alba. Methods: The antibacterial activity of leaves and roots of Eclipta alba was evaluated by agar well diffusion method and minimum inhibition concentration against different bacterial species such as Bacillus subtilis, Escherichia coll, Klebsiella pneumoniae, Pseudomonas fluorescens. Staphylococcus aureus and Shigella flexneri. Results: 20 pi of chloroform extract of leaves and root powder of Eclipta alba was found to exhibit best inhibitory activity against Klebsilla pnemoniae such as 32 mm and 35 mm respectively when compared to other solvents and hot aqueous extract. Leaves of benzene extract exhibited good inhibitory zone of 25mm against Shigella flexneri and growth of Bacillus subtilis was inhibited up to 28mm by chloroform extract of root. All tested organisms exhibited lowest zone of inhibition between 8-lOmm with acetone, methanol and aqueous extract of both leaves and roots of Eclipta alba. MIC was between concentration of 8-0.25mg/ 100 pi with all tested bacteria. From the results, it is clear that the extracts of leaves and root of Eclipta alba possess potential broad spectrum antibacterial activity.
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    Antibacterial Activity of the Leaves, Bark, Seed and Flesh of Moringa Oleifera
    (2011) Gayathri Devi, S
    Moringa oleifera belongs to an onogeneric family of shrubs and tree, Moringaceae. In the Dravidian language there are many local names for Moringa oleifera but all are derived from the generic root "Morunga". It has anticancer, anti-inflammatory activity and thyroid status regulator efficacies. An experiment was carried out to study the antibacterial activity of different solvent extracts of Moringa oleifera plant by agar well diffusion method against Bacillus subtilis, Escherichia coli, Klebsiella pnemoniae, Shigella dysentriae and Staphylococcus aureus that frequently cause enteric infections in humans. The benzene, methanol and aqueous extracts of Moringa oleifera leaves, bark, seed and flesh have shown strong antibacterial activity against all the organisms tested such as B. subtilis, E. coli, K. pneumoniae. S. dysentriae and S. aureus. The zone of inhibition ranged from 7-23mm. The plant Moringa oleifera can be used as a source of oral drugs to fight infections caused by susceptible bacteria.
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    Antioxidant Activity of Acafypha indica
    (2011) Gayathri Devi, S
    The present study was carrie^'to explore the antioxidant activity of leaves and roots of ^ calypha indica. The study was designed to evaluate the en2ymic and Aon enzymic antioxidant status and in vitro free radical scavenging effects ofAcalypha indica. The leaves and roots o^Acafypha indica were found to have appreciable amounts of enzymic and non-enzymic antioxidants. The benzene, chloroform, acetone and methanol extracts exhibited potent in vitro free radical scavenging activity. Therefore, Acafypha indica leaves and roots can be used for treatment of diseases caused by free radicals (Keywords: Enzymic antioxidants, non-enzymic antioxidants, free radical scavenging activity).
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    Antioxidant Activity of Acalypha indica
    (2011) Gayathri Devi, S
    The present study was carried to explore the antioxidant activity of leaves and roots olAcalypha indica. The study was designed to evaluate the enzymic and non enzymic antioxidant status and in vitro free radical scavenging effects of Acalypha indica. The leaves and roots of Acalypha indica were found to have appreciable amounts of enzymic and non-enzymic antioxidants. The benzene, chloroform, acetone and methanol extracts exhibited potent in vitro free radical scavenging activity. Therefore, Acalypha indica leaves and roots can be used for treatment of diseases caused by free radicals (Keywords: Enzymic antioxidants, non-enzymic antioxidants, free radical scavenging activity).
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    Antioxidant and Antibacterial Activity of Acalypha Indica
    (2010-05) Tamilarasi , K; Gayathri Devi, S
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    Antioxidant Potential And In Vitro Free Radical Scavenging Activity Of Aerva lanata
    (2011) Gayathri Devi, S
    In this paper the enzymic antioxidants (catalase, peroxidase, glulathione-s-transferase, glutathione reductase and superoxide dismutase) and non-enzyniic antioxidants (ascorbic acid, a tocopherol, carotenoids, flavonoids and polyphenols) of the flower and root of Aerva lanata are discussed. The free radical scavenging activity, of different extracts of Aerva lanata was analyzed. The results showed that the extracts form a good source of all the antioxidants analysed and identified.
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    Antioxidant Potential of the Leaves and Roots of Solanumsura Ttense
    (2010) Gayathri Devi, S
    Solanum surattense is phenotypically highly polymorphic species and extensively used traditionally by the tribal people as anthelmintic, diuretic, antiarrhythmic, hypotensive, expectorant and carminative. The present study was assessed to evaluate the in vitro antioxidant activity in the leaves and roots o f Solanum surattense. The enzymic antioxidants such as catalase (CAT) superoxide dismutase (SOD), glutathione reductase (GR), glutathione S-transferase (GSH) and glutathione peroxidase (GPX) and non enzymic antioxidants (ascorbic acid, a-tocopherol, reduced glutathione, flavonoids and carotenoids) were found to be present. The free radical scavenging activity such as inhibition o f DPPH radical, in vitro lipid peroxidation, inhibition of superoxide generation and nitric oxide generation and hydrogen peroxide scavenging activity o f different extracts of Solanum surattense were also assessed. The results obtained in the present study indicated that the Solanum surattense might be a good source o f natural antioxidant.
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    Antioxidant Properties of the Leaves and Stems of Aristolochia Indica
    (2009-04) Priya, V; Gayathri Devi, S
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    Antioxidant Properties of the Leaves and Stems of Aristolochia Indica
    (2010) Gayathri Devi, S
    Aristolochia indica is a traditionally used medicinal plant claimed to possess antioxidant, antidiabetic and anti-inflammatory activity. The present study was conducted with the purpose to evaluate the in vitro antioxidant activity in leaves and stem of Aristolochia indica. The enzymic antioxidants such as catalase (CAT), superoxide dismutase (SOD), glutathione reductase (GR), glutathione peroxidase (GPx) and glutathione-s-transferase (GSH) and non-enzymic antioxidants (ascorbic acid, atocopherol, reduced glutathione, total carotenoids and flavonoids) were found to be present. The free radical scavenging activity (inhibition of nitric oxide and super oxide generation, in vitro lipid peroxidation and DPPH free radical scavenging and hydrogen peroxide radical scavenging activity) of different extracts of Aristolochia indica was also observed. The results obtained in the present study indicated that the Aristolochia indica might be a good source of natural antioxidant
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    Antioxidant Properties of the Leaves And Stems of Aristolochiaindica
    (2010) Gayathri Devi, S
    Aristolochia indica is a traditionally used medicinal plant claimed to possess antioxidant, antidiabetic and anti-inflammatory activity. The present study was conducted with the purpose to evaluate the in vitro antioxidant activity in leaves and stem of Aristolochia indica. The enzymic antioxidants such as catalase (CAT), superoxide dismutase (SOD), glutathione reductase (GR), glutathione peroxidase (GPx) and glutathione-s-transferase (GSH) and non-enzymic antioxidants (ascorbic acid, atocopherol, reduced glutathione, total carotenoids and flavonoids) were found to be present. The free radical scavenging activity (inhibition of nitric oxide and super oxide generation, in vitro lipid peroxidation and DPPH free radical scavenging and hydrogen peroxide radical scavenging activity) of different extracts of Aristolochia indica was also observed. The results obtained in the present study indicated that the Aristolochia indica might be a good source of natural antioxidant.
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    Comparative Evaluation of Free Radical Scavenging Activity of Cleome Viscose and Trichodesmaindicum
    (2014) Gayathri Devi, S
    Objective: The present study was attempted to compare the in vitro free radical scavenging activity in the leaves, fruits and roots of Cleome viscose and Trichodesmaindicum. Methods: The leaves, fruits and roots of Cleome viscose and Trichodesmaindicum were extracted with solvents namely petroleum ether, benzene, chloroform, ethyl acetate and ethanol for the determination of free radical scavenging activity. The antioxidant activity was evaluated by determining ABTS, DPPH, superoxide, nitric oxide, hydroxyl radicals, hydrogen peroxide scavenging and inhibition of in vitro lipid peroxidation. Results: The chloroform and ethyl acetate extract of the roots of Trichodesmaindicum and the ethyl acetate extract of the fruit of Cleome viscose exhibits strong inhibition against DPPH radicals. The ethyl acetate and ethanol extract of the leaves, fruits and roots of Cleome viscose and ethanol extract of the leaves, fruits and roots of Trichodesmaindicum showed signi icant ABTS radical scavenging activity. Petroleum ether extract of the leaves of Cleome viscose and Trichodesmaindicum was found to possess potent superoxide scavenging activity. The maximum nitric oxide scavenging activity was found to be exhibited by the benzene extract of the fruit of Trichodesmaindicum. Ethyl acetate and benzene extract of the leaf of Trichodesmaindicum reveals the signi icant activity of hydroxyl radical scavenging activity. Conclusion: Based on the results, it can be concluded that the extracts of both the medicinal plants Cleome viscose and Trichodesrr,aindicum have great potential of free radical scavenging activity.
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    Comparative Evaluation of Phytochemicals and Antioxidant Potential of Cleome viscose and Trichodesma indicum
    (2013) Gayathri Devi, S
    Cleome viscose and Trichodesmaindicumare \A/ell-known medicinal plants. There leaves, fruits and root extracts were obtained and investigated for their total phenols, flavonoids and alkaloids contents respectively. The enzymic (catalase, peroxidase, polyphenol oxidase, superoxide dismutase and glutathione-S-transferase) and non-enzymic (ascorbic acid, a-tocopherol, reduced glutathione and flavonoids) antioxidant components were determined by using standard protocols. It was found that all the phytochemicals analysed were present in both the fruit and root of Cleome viscose and Trichodesmaindicum. The leaves of Cleome viscosa did not show the presence of alkaloids and the leaves of Trichodesmaindicum did not found to contain the flavonoids. The activity of cataiase was higher in the fruits (118.9±5.6 U/g) of Cleome viscosaand leaves (117±4.1 U/g) of Trichodesmaindicum. In the case of peroxidase and glutathione-S- transferase the maximum result was shown by both the fruits and roots of Cleome viscose and Trichodesmaindicum. A significant non-enzymic antioxidant activity was found in both the plants. From the present study it is evident that the leaf, fruit and root extracts of Cleome viscose andTrichodesmaindicum possess good antioxidant activity. Hence the plant can be further explored to be used as a potent therapeutic agent for free radical related pathological damage.
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