Antibacterial Activity of Leaves and Roots of Eclipta Alba
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Date
2014
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Abstract
Objective: The present study was aimed to investigate the antibacterial activity of leaves and roots of Eclipta alba.
Methods: The antibacterial activity of leaves and roots of Eclipta alba was evaluated by agar well diffusion method and minimum inhibition
concentration against different bacterial species such as Bacillus subtilis, Escherichia coll, Klebsiella pneumoniae, Pseudomonas fluorescens.
Staphylococcus aureus and Shigella flexneri.
Results: 20 pi of chloroform extract of leaves and root powder of Eclipta alba was found to exhibit best inhibitory activity against Klebsilla
pnemoniae such as 32 mm and 35 mm respectively when compared to other solvents and hot aqueous extract. Leaves of benzene extract exhibited
good inhibitory zone of 25mm against Shigella flexneri and growth of Bacillus subtilis was inhibited up to 28mm by chloroform extract of root. All
tested organisms exhibited lowest zone of inhibition between 8-lOmm with acetone, methanol and aqueous extract of both leaves and roots of
Eclipta alba. MIC was between concentration of 8-0.25mg/ 100 pi with all tested bacteria. From the results, it is clear that the extracts of leaves and
root of Eclipta alba possess potential broad spectrum antibacterial activity.