Anti-inflammatory and antioxidant activity index of the aerial roots of Rhaphidophora aurea (Linden Ex Andre) intertwined over different host trees

Simple item page
dc.categoryJournal Article
dc.contributor.authorLalitha, P
dc.date.accessioned2017-08-29T08:22:12Z
dc.date.available2017-08-29T08:22:12Z
dc.date.issued2014
dc.departmentChemistryen_US
dc.description.abstractRhaphidophora aurea is a common ornamental plant with aerial roots required for its support. It climbs over host trees and sucks the nutrients of the host. A similar species Epiprenum pinnatum is reported to possess anticancer activity. The leaves of Rhaphidophora aurea are toxic but there are no reports on the uses of aerial roots. The weird property of the aerial roots to twine over the host and suck its nutrients persuaded us to explore the properties of the host and uncover the acquired therapeutic properties of the aerial roots of Rhaphidophora aurea. Materials and methods: The antioxidant activity index of various solvent extracts of the aerial roots of Rhaphidophora aurea intertwined over four different host trees were evaluated by DPPH radical scavenging method and reducing power assay. IC50, EC50 and antioxidant activity index (AAI) were taken up for antioxidant assessment. The ethyl alcohol extract of the aerial roots of Rhaphidophora aurea twined over Lawsonia inermis (MM) and Areca catechu (MB) were tested for anti-inflammatory activity in formalin induced Swiss Albino mice paw oedema model and the paw thickness was measured each one hour upto six hours. Results and Conclusions: Among all the extracts evaluated, the ethyl alcohol extract of the aerial roots of Rhaphidophora aurea twined over four host trees specially Azadirachta indica (MN) exhibit higher antioxidant activity with a strong AAI (5.29) as compared to AAI (2.74) of standard Ascorbic acid. In formalin induced inflammation model, the dose (100mg/kg) produced significant percentage inhibition of mice paw oedema compared to control group. It can be concluded that alcoholic extract of aerial roots of Rhaphidophora aurea intertwined over four different host trees shows good in vitro antioxidant and in vivo anti-inflammatory activity and hence of good promise in pharmaceutical field.en_US
dc.identifier.issn0974-6943
dc.identifier.urihttps://ir.avinuty.ac.in/handle/avu/3505
dc.langEnglishen_US
dc.publication.categoryJournal Articleen_US
dc.publisher.nameJournal of Pharmacy Researchen_US
dc.publisher.typeInternationalen_US
dc.titleAnti-inflammatory and antioxidant activity index of the aerial roots of Rhaphidophora aurea (Linden Ex Andre) intertwined over different host treesen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Chem_2014_033.pdf
Size:
87.16 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Journal Article