Antimicrobial Activity of Some of Chlorocobaloximes Containing Axial Substituted Pyridines
No Thumbnail Available
Date
2011
Authors
Amutha Selvi, M
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Cobaloximes o f the type [Co(dmgH)2(B)Cl] ; where, (ImgET = dimethyl glyoximate, B= 3-
chlorpyridine (3-PyCl), 3-bromopyridine (3-PyBr), 4-aminopyridine (4-AP), 4-methylpyridine
(4-MP), 4-N,N’-dimethyl aminopyridine (4-DMAP) and 4-cyanopyridine (4-PyCN) were
prepared, characterized by the usual .spectroscopic techniques and screened agaimt
microorganism for antimicrobial activity with ciprofloxacin as standard. The cobaloximes were
found to be active against most o f the microbes. Die cobaloxime containing 4-cyanopyridine as
the axial ligand showed potential inhibition; whereas, the complex [Co(dmgH)2(3-PyCl)Cl]
showed the least microbial growth.