Antibacterial Activity of Selected Medicinal Plant in Traditional Treatment of Wound Infection in Southeast India
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Date
2014
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Abstract
Objective: The wound healing potential of fruit peel of Pithecellobium dulce Benth, a plant traditionally used for wound treatment against woundinfecting
bacteria, was assessed using disc diffusion and microtitre plate methods.
Methods: P. duke fruit peel was extracted using ethyl acetate, methanol and water and tested for their antimicrobial activities against bacterial
isolates from wound infection using disc diffusion and microtitre plate methods.
Results: All the three extracts had antimicrobial activities, among which methanol extract had higher activities against all the tested organisms
compared to the ethyl acetate and aqueous extracts. The most susceptible organism to all the extracts was K pneumonia and S. aureus while the
most resistant were P. mirabilis and P. vulgaris.
Conclusion: The potential antibacterial activity of P. dulce plant against both gram-positive and gram-negative bacteria justifies the use of the plant
as the wound healing agent. The isolation of active principle of this plant may serve as source and lead for the synthesis of drugs in pharmaceutical
industries.