Antifungal Activity of Beterocycles Sinthesized Under Microwave Radiation
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Date
2010
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Abstract
Quinoline compounds posses? a wide rarvae. :i
antibscierial, ar.tifungai and antimoxagenic properties. Tr.e
present work Involves synthesis of three heterocycies-4-
p’henyi 5-vinyi quinotin-2-on8 (1), 4-phenyl-3-ch!oroqijinoline
(2), 4-phenyl-3-vinyl quinoline-2-thlone (3)
utilizing microwave technology and testing their antifungal
activity against 4 fungi namely Aspergillus flavus, Rhizopus
nigricans, Mucor hiemaiis and Candida albicans. Antifungal
studies of compounds showed good fungal activity. The
antimicrobial significance of the synthesized compounds is
we!! evident from the study.