Lipophilicny of Few Chromen-2-Ones And Chromene-2-Th10nes By Hyperchem 7.0 And Alogps 2.1
| dc.category | Journal Article | |
| dc.contributor.author | Lalitha, P | |
| dc.contributor.author | Jayanthi, P | |
| dc.date.accessioned | 2017-02-17T00:54:32Z | |
| dc.date.available | 2017-02-17T00:54:32Z | |
| dc.date.issued | 2011 | |
| dc.department | Chemistry | en_US |
| dc.description.abstract | Lipophilicity which plays an important role in researcm,i^^th^r'structure-activity relationship of drug action has been theoretically predictl^^for fev^chromen-2-ones and chromen-2-thiones using commercial software ^^HyperCft^’>'7.0 and an internet computational software ALOGPS 2.1. In the compoiiij^s ana.lj^ed for lipophilicity using HyperChem, the compounds possessing -NO^.grou]^ s h p ^ d a negative log P value. The log P values of alt the other compounds, wey^;' " ‘ to .l.i.e. ...w...i.t.h..i n 3- . T—heoretical determination of lipophilicity reduces the tim'd .involve'd in calculation of lipophilicity by experimental methods. ALOGPS 2.1 waTcpmparatively greater than that calculated using HyperChem. | en_US |
| dc.identifier.uri | https://ir.avinuty.ac.in/handle/avu/1417 | |
| dc.lang | English | en_US |
| dc.publisher.name | AN INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES | en_US |
| dc.publisher.type | International | en_US |
| dc.title | Lipophilicny of Few Chromen-2-Ones And Chromene-2-Th10nes By Hyperchem 7.0 And Alogps 2.1 | en_US |
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