Antitumor Activity of Methanolic Extract of Terminalia Catappa Leaves Against Ehrlich Ascites Induced Carcinoma In Mice

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dc.categoryJournal Article
dc.contributor.authorAnnapurani, S
dc.date.accessioned2017-03-08T21:59:57Z
dc.date.available2017-03-08T21:59:57Z
dc.date.issued2011
dc.departmentBiochemistryen_US
dc.description.abstractTerminalia catappa belongs to the family combretaceae and is popularly known as badam.lt is a well known herb in Ayurvedic system of medicine The aim of the present study is to evaluate the effect of methanolic extract of leaves of Terminalia catappa against Ehrlich ascetic Lymphoma (ELA) in Swiss albino mice.The tumor was induced in mice by intraperitoneal injection of ELA cells (lX106cells/mice). Methanolic extract of Terminalia catappa was administered to the experimental animals at a dose of 75pg/kg/day after 24 h of tumor inoculation. The antitumor effect of extract was evaluated by assessing in vitro cytotoxicity, increase in lifespan, hematological parameters and liver enzymes. The methanolic extract brought back the altered levels of the hematological parameters and liver enzymes. Thus the present study revealed that methanolic extract of Terminalia catappa possessed significant antitumor activity.en_US
dc.identifier.urihttps://ir.avinuty.ac.in/handle/avu/1977
dc.langEnglishen_US
dc.publisher.nameINTERNATIONAL RESEARCH JOURNAL OF PHARMACYen_US
dc.publisher.typeInternationalen_US
dc.titleAntitumor Activity of Methanolic Extract of Terminalia Catappa Leaves Against Ehrlich Ascites Induced Carcinoma In Miceen_US
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