Cytotoxic properties of Acorns calamus in MCF -7 breast cancer cells

dc.categoryJournal Article
dc.contributor.authorSanthy, K S
dc.date.accessioned2017-01-12T22:53:19Z
dc.date.available2017-01-12T22:53:19Z
dc.date.issued2013
dc.departmentLife Science - Zoologyen_US
dc.description.abstractIn this study cytotoxic effect of Acorus calamus extract was evaluated on breast carcinoma (MCF-7) cell lines. MCF-7 cells were cultured in DMEM medium and incubated with different concentrations (18.75, 37.5, 75, 150 and 300 |tg/ml) of Acorus calamus methanol extract. Cell viability was assessed by MTT assay. Acorus calamus decreased cell viability in malignant cells in a concentration dependent maimer. The IC50 values in MCF-7 cells were determined as 52.07 pg/ml. It may be concluded that Acorus calamus can cause cell death in MCF-7 cancer cells which can be considered as a promising chemotherapeutic agent in breast cancer treatment.en_US
dc.identifier.urihttps://ir.avinuty.ac.in/handle/avu/1063
dc.langEnglishen_US
dc.publisher.nameIntemationaCJoumaC o f Current ^search andAcademic Reviewen_US
dc.publisher.typeInternationalen_US
dc.titleCytotoxic properties of Acorns calamus in MCF -7 breast cancer cellsen_US
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