Antioxidative Activity of Methanolic Extract of Gloriosa Superba Seed, Tuber and Leaves
No Thumbnail Available
Date
2013
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Medicinal plants play a key role in the human health care. About
eighty percent of the world populations rely on the use of traditional
medicine, which is predominantly based on plant materials. The
present study was carried out to evaluate the antioxidative activity of
methanolic extract of Gloriosa superba seed, tuber and leaves
(MEGSSTL). The percentage radical scavenging of MEGSSTL on DPPH
and the IC50 (50% inhibitory concentration) value was found to be 38,
52 and 74 pg., hydrogen peroxide scavenging activity of MEGSSTL and
the IC50 value was found to be 50, 63 and 68 pg., nitric oxide
scavenging activity of MEGSSTL and the ICso value was found to be the
61,71 and 84 pg., hydroxyl radical scavenging ability of MEGSSTL to
50 percent was found to be 70,76 and 85 pg (ICso) ond superoxide
radical production in vitro in a dose dependent manner with an IC50 of
58,70 and 75 pg. respectively. The dose dependent percentage
scavenging activity of DPPH, hydrogen peroxide, nitric oxide, hydroxyl
and superoxide radical by methanolic extracts indicated its
antioxidative efficacy.