Challenging Issues and Technological Approaches in Medicine
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Date
2016
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Abstract
Ethnobotanical alternates for synthetic allopathic drugs are soon gaining importance in the treatment of
leases due to their Fewer side eflects. Acorus calamus has been widely used globally due its richness in antioxidant frtoconstituents in the treatments yielding beneficial functions. The methanol extract obtained by soxhlet
faction was screened for acute toxicity studies on DAL induced cells. Accordingly 100 and 200 mg/kg body
ight were taken as low and high dose of MEAC for the histopathological studies on liver and kidney.In the (sent study the damage induced by DAL cells in the liver sections were partially reversed by the A. calamus
fact treatment. The kidney histopathology micrograph of DAL induced mice showed marked tubular and
bmerular damage. This damage is regenerated by the treatment with methanol extract of A.calamus. The protective
teci of A.calamus against liver and renal cell injury induced by DAL cells might be attributed to its antioxidant
pion.