Free Radical Scavenging Activity of Metallothioneins from Peripheral Blood Lymphocytes of Gold Jewellery Karigars

dc.category	Journal Article
dc.contributor.author	Jeyanthi, G P
dc.date.accessioned	2017-03-09T18:51:42Z
dc.date.available	2017-03-09T18:51:42Z
dc.date.issued	2014
dc.department	Biochemistry	en_US
dc.description.abstract	Metallothioneins (MT) are cysteine rich, low molecular weight metal binding proteins involved in deto.xification and homeostasis of metals. Due to a variety of chemical stresses MTs are stimulated and can be used to assess human exposure to occupational agents. Human Peripheral Blood Lymphocytes (PBLs) have the ability to produce MTs against occupational exposure to silver (Ag). In the present study. PBLs were isolated from the blood of gold jewellery unit workers and MT was separated by sephade.x G-75 gel filtration. Molecular mass of MT was determined by SDS-PAGE using silver staining method from the collected fractions. HPLC was performed to measure the levels of MT from the collected fraction, it is suggested that the elevated levels of MT in PBLx can he used as specific indices of .silver e.xposure.	en_US
dc.identifier.uri	https://ir.avinuty.ac.in/handle/avu/2049
dc.lang	English	en_US
dc.publisher.name	International Research Journal of Medical Sciences	en_US
dc.publisher.type	International	en_US
dc.title	Free Radical Scavenging Activity of Metallothioneins from Peripheral Blood Lymphocytes of Gold Jewellery Karigars	en_US

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