Santhy, K S2017-01-232017-01-232015https://ir.avinuty.ac.in/handle/avu/1092In recent years, metal nanoparticles li.ive received considerable attention III pharmaceutical applications. I’hese n.I noparticles can be synthesized either I hcmically or biologically. Biological synthesis of nanoparticles is less time I onsuming, less Mostly and more eco Inendly. In the present study, the green synlhesis of selenium nano particles from the Solanum torvum fruit extract has been tallied out and characterized by UV-Vis sfx'clra, SEM and FTIR analysis. The anliniicrobial activity of the synthesized ScNI’s against various pathogens and also the cytotoxic activity against MCF-7 breast I .nicer cell line were determined. Solanum u >1 1 um fruits (sundaikkai) were collected in November and December 2013 from the local areas of Coimbatore. The functional groups were observed in the sample tilling FTIR analysis. The SEM image was analyzed to confirm the particle size and .tpjiearance of club formed at 93nm. The itniimicrobial activity was screened against I-coll. Bacillus sp.. Pseudomonas sp. and Kh'hsella sp. The maximum activity occurs at 2mM concentration of selenium naiioparticles. Exposure to increasing Concentration of SeNPs showed dosedependent cytotoxicity on MCF-7 cells.These results throw light on the potent anticancer activity of Solanuin torvum mediated selenium nanoparticles.