Gayathri Devi, S2017-03-092017-03-092013https://ir.avinuty.ac.in/handle/avu/2038Cleome viscose and Trichodesmaindicumare \A/ell-known medicinal plants. There leaves, fruits and root extracts were obtained and investigated for their total phenols, flavonoids and alkaloids contents respectively. The enzymic (catalase, peroxidase, polyphenol oxidase, superoxide dismutase and glutathione-S-transferase) and non-enzymic (ascorbic acid, a-tocopherol, reduced glutathione and flavonoids) antioxidant components were determined by using standard protocols. It was found that all the phytochemicals analysed were present in both the fruit and root of Cleome viscose and Trichodesmaindicum. The leaves of Cleome viscosa did not show the presence of alkaloids and the leaves of Trichodesmaindicum did not found to contain the flavonoids. The activity of cataiase was higher in the fruits (118.9±5.6 U/g) of Cleome viscosaand leaves (117±4.1 U/g) of Trichodesmaindicum. In the case of peroxidase and glutathione-S- transferase the maximum result was shown by both the fruits and roots of Cleome viscose and Trichodesmaindicum. A significant non-enzymic antioxidant activity was found in both the plants. From the present study it is evident that the leaf, fruit and root extracts of Cleome viscose andTrichodesmaindicum possess good antioxidant activity. Hence the plant can be further explored to be used as a potent therapeutic agent for free radical related pathological damage.